Go to Kouan Bus Station(口岸汽车站) and take long distance bus to Guangzhou Bus Station(广州汽车站), there are buses to various destinations to Guangzhou, remember you need to take bus to Guangzhou Bus Station. On the way, alight at Haizhu Plaza Station (海珠广场), there walk around 10 minutes to your hotel.

From Hotel to Hong Kong, you can walk to Hotel Landmark and take direct bus to Hong Kong, the bus timetable is from 05:15 to 20:40 with around 30 minutes interval. For this bus, you can alight at Metropark hotel Mong Kok, this hotel is around 600 meters to Royal Plaza Hotel.