Besides of the expensive helicopter from Hk Airport to Macau, the other transportation between these two cities is the frequent ferries. The New World Center is close to the China Hong Kong City Terminal, where the ferries depart to Macau at 07:00~22:30 once every 30 miutes. You could take a taxi to the terminal quickly or the buses of 215x and 110 for two stations.

There are so many hotels in Macau, I suggested that you look for one in the commercial center so that you could feel this city well. It seems that two bedrooms are needed for you. The Venetian Macao-Resort Hotel, the Hotel Lisboa, the Galaxy Starworld Casino and the 3-star Emperor Hotel enjoy high fame during travelers. And, most of the hotels supply free shuttle bus from the Macau port to the hotels.