How to go macau from California hotel in nathan road?

From the hotel, take Tsuen Wan Line at Tsim Sha Tsui Station, get off at Central Station. Then transfer to Island Line to Sheung Wan Station, Exit D. It takes around 20 mins on the way. The ticket fare is 9.4 HKD per person. Afterwards, walk northeast to get to HK-Macau Ferry Terminal. There are many direct ferries that can take you Macau.