Night buses from Guangzhou airport to southern train station

Well, there is no direct shuttle bus that can take you to the South Railway Station.
What's your landing time? If you land at the airport after 01:00, there is only shuttle bus line 1 at that time. You can take it and get off at Airport Ticket Office. The operating hours of this bus route will until the arrival of the last flight. After arriving, get a cab to go to the destination. The cab fare will be CNY 75 to 85 at night.