Is this located at 3146, Renmin North Road, Luohu district? If so, please follow my suggestion:

When you arrive at Hong Kong Airport, please follow the directions to the intercity bus counter where you could catch a coach to arrive in downtown Shenzhen directly. Please remember to take the bus which departs to Luohu Hotel, Shenzhen. When you arrive at this hotel, you could take a cab to the Shenzhen Marster Hotel (Hong Hu Branch)directly. It is just 2kms away.

The bus shedule could be search here: http://www.hongkongairport.com/CBT/Controller?locale=eng

Thanks Mr Jamie for your kind reply to my query.
The hotel address is Shenzhen Master Hotel, No: 183 Taining Road,
Luhou District.

Is the direction given by you to this correct address.
Would appreciate if you can tell me whether I need to prebook the coach seats from Hong Kong Airport to Shenzhen Luhou Hotel.
Thanks once again.

It is not the same hotel in Renmin North Road, but actually, these two hotels are not far from ech other. You can follow the route either and take taxi from Luohu Hotel or Luohu Station to the hotel. Generally speaking, you do nnot need to prebook the seat.