There are two methods available:
1. you could catch a bus from Shenzhen Airport to arrive in downtown Guangzhou directly. Please refer to the info at https://www.travelchinaguide.com/cityguides/guangdong/shenzhen/airport-terminal.htm
2. if you miss the bus, please take the shuttle bus Line 1 to Shenzhen Railway Station, where you could catch a train to arrive in Guangzhou in 70 minutes. Then, you could transfer to the metro or cab to get to Shangxiajiu Road.