Which station (Nanjing Railway Station or South Station) is closer to The Mingfa Pearl Spring Hotel?

The Main Railway Station is nearer to the hotel, about 12 miles (20km). You can take bus line 558 to North Puzhu Road, South Liuzhou Road Station. Then, change to bus line 568 to the west gate of Pearl Spring Park, and you can see it.

If by taxi, the fare may be around CNY 50-60. ;)