I want to go from Huai'An, Jiangshu to Shanghai on Wednesday, September 23, 2015

Flight are available for Wednesday. But they are not direct flights. You need to transfer at Nanjing or Beijing.
So it's suggested to take direct long-distance bus from Huaian South Bus Station, get off at Shanghai General Bus Station. The schedules are from 06:30 to 17:00 with the ticket fare of CNY 128 per person. And the duration is about 6 hours.