Visit to Wuzhen going from Shanghai to Hangzhou on Sunday 19 October

At Shanghai South Long-distance Bus Station, which is near the South Railway Station, you can take a direct bus to the water town. After sightseeing there, there are direct buses to Hangzhou.

Well, I've been there last month. WZ is an ancient town with beautiful scenery and friendly residents. The suggested sightseeing time is one day. If you have enough time, you can stay one night in the scenic area, because nightscape of this place is quite famous. Then next day, you can go to Hangzhou.