There are air-conditioned buses operating between Macau and Guangzhou, which should pass the Barrier Gate and Gongbei Border. Barrier Gate, located at the northern end of the Macau is the main entry gate to Zhuhai in Guangdong Province.
The place to board these buses is the Kee Kwan's Company bus stop, close to Master Hotel in Macau. However, the bus company is not responsible for Chinese tourist visa which travelers have to hold in order to cross the border from Macau to Zhuhai. Make sure to get all your documents well prepared for border crossing. For travelers who have not yet applied for their Chinese visa, the alternative is to firstly exit Macau from the Barrier Gate and take immigration formalities at Gongbei Border, and then catch the buses at Gongbei to Guangzhou.