In the last week of October, there is only flight information for October 26; conjoint flights provided by Uzbekistan Airlines and Pakistan International Airlines by which you need to transfer twice. Normally, there are direct flights provided by China Southern Airlines on Wednesdays and Sundays. Maybe China Southern Airlines has not published the flight information of that time. I suggest you wait for a few days, at most till the end of September.

Here is the direct flight on October 4 (Sunday), 2009 for your reference:
Urumqi – Islamabad, 09:30-10:00, China Southern Airlines, flying time: 2.5 hours
The lowest airfare for the day is CNY1,310 excluding any tax. But the discount varies greatly daily.