Are there any direct bus from WUXU airport to Guilin? If yes, how long does it take?

Sorry, there isn't. First, you can go to Langdong Bus Station: Take shuttle bus line 4 to Crowne Plaza Nanning City Center station, then transfer to metro line 1 from Dongmeng Business district station to it (Exit C). Next, you can take direct bus from Landong Bus Station to Guilin at 10:05 and 16:40.