Fastest way to travel from Hong Kong Airport to Guangzhou China Hotel A Marriott Hotel

Well, you can take a ferry at 15:20 to Lianhuanshan Port, Guangzhou. It takes about 100 minutes and 300HKD.
After that, take a taxi to Haibang Subway Station. Then, take subway line 4 and transfer to line 8 at Wanshengwei. Do another transfer to line 2 at Changgang, and get off at Yuexiu Park. Leave from Exit D1/D2, you will see the hotel.

Thanks for the reply and the recommendation. However, I thought that was a complicated way by ferry + taxi + 3 times MRT transfer before arriving at destination. I was cheated twice when travelling by taxi in Guangzhou and I don't think I would take taxi anymore if I could help it.

I understand there is a couch/bus service with direct connection from Hong Kong airport to Guangzhou city ? I also gather that there is one type without having to change to another at the immigration ?

Look forward to your further reply.

Yes, there is a direct bus to your hotel, and it takes about 3h 30 minutes, 250HKD. Follow the signs, you can find the bus station easily. Also, you can turn to the staff for help! Have a nice trip!