I'm thinking of going to Ngong Ping 360 to take the cable car. Can I go on single trip ?

Certainly! You can take a single trip! After sightseeing, you can take bus line 23 from Ngong Ping Station to Tung Chung Town Center Station. The bus ride takes 50 minutes, and costs HKD 17.2. Then, take MTR Tung Chung Line from Tung Chung Station to Lai King Station, and switch to MTR Tsuen Wan Line to Tsim Sha Tsui Station. The metro ride takes takes 40 minutes, and costs HKD 16.9. :)