From Guangzhou Liede Metro Station, which is the nearest bus station I can go to Hong Kong?

Well, you are suggested to take a taxi from Lide Metro Station and get off at Yutong Hotel first. The cab fare is about CNY 20 in usual time. After arriving, there are several direct long-distance buses that can take you to HK. The bus schedules are 07:20, 07:30, 07:40, 07:50 and 08:00. It costs CNY 100-120/person to HK downtown area.