How can I get from Hangzhou east railway station to Zhejiang Hotel?

Well, there is no direct public transportation. You are suggested to take subway line 1, get off at Longxiangqiao Station, Exit B3. Then transfer to bus no.27 to Zhejiang Hotel directly.
Or from the East Railway Station, just take a taxi to the hotel. The cab fare would be around CNY 35 in the day time.