Is there a speed train from Lanzhou to Jiayuguan ?

Yes, you can take high-speed train from West Railway Station, and arrive at Jiayuguan South Railway Station. The schedules are 07:40, 07:55, 08:12, 08:30, 09:20, 09:38, 10:50, 11:53, 12:10, 13:33, 13:45, 17:10 and 17:45. The second class seat costs CNY215 and first class seat costs CNY258. It takes around 4.5 to 7 hours on the way.