Hello I want to Guangzhou from Shenzhen, I plan by speed train ,

If you take the G-trains, you will reach GZ South Railway Station. Then yo can take the local subway line 2 to reach local Railway Station. Then you can get out of the station from Exit G and walk along Zhannan Road to reach Zhanqian Road. Then you can walk along Zhanqian Road to reach your hotel directly.
If you take the D-trains, you will reach GZ East Railway Station and then take the subway line 3 to reach Zhujiang New Town Station where you can change to line 5 to reach local Railway Station. Then you can find the way I mentioned above to find your hotel.