what is the fastest way to travel from panyu, Guangzhou to shenzhen bay or shekou?

From Panyu, there is no direct buses to reach Shekou. It is suggested to go to the local provincial bus station to take the direct buses.
From Panyu, you take the subway line 3 to reach Zhujiang New Town where you can change to line 5 to reach the local railway staton. Then you can easily find the provincal bus station. There the buses for Shekou is frequent.