Shenzhen Perthden Hotel is close to the Luohu port, which closes at 24:00. So you would better reach Shenzhen by getting through Huanggang Port. From HK airport, you can take the airport bus A43 to Shangshui first and then take a bus to Huanggang Port that is opening 24hrs. Passing the port, you can take a taxi to the hotel with cost around CNY20.